Again: "Out of 9 cases of cholera, and 13 of the worst cases of diarrhoea occurring in my own practice, and treated with chloroform, _one died_. All these were in the better ranks of life. In some of them, the warm bath (salt water) was used as an auxiliary, and the diet consisted of nothing but cold milk and water, with some carbonate of soda, _ad libitum_. The fatal case was that of a drunkard, who, probably, did not take the remedy. These cases varied in severity, from sickness and diarrhoea, and mild collapse, to sickness, diarrhoea, severe cramps, and great collapse, with almost clear watery evacuations, passing away involuntarily * * * Of 14 cases of cholera treated by Mr. Towers, Medical Resident of the Infirmary, many of them under my own observation, _one died_. The fatal case was that of a woman aged 63, who was previously suffering great depression, consequent on extreme destitution." Again, says Dr. Davies, "It will probably be remembered that, in my second report, I expressed a very favorable opinion of chloroform in this deadly malady. I considered I had strong grounds for so doing, after observing the large proportion of cases which recovered under its administration. From the history of this last visitation in the county prison, however, the fact turns out, that, under some uncertain circumstances, the use of chloroform will not prevent the proportion of deaths being considerable. I have reason to believe that it was, from over-anxiety, given in too frequent doses in some cases, and that it thus rather added to the coma, which is one of the characteristics of the malady. At the commencement of the outbreak, the doses were repeated every hour, or every two hours, and it is to be noted that the first seven cases _recovered_. As the cases multiplied, the remedy was given every half hour, and, in some instances, every quarter of an hour; the result was that the next six cases died. Whether these cases had anything in them inherently more fatal, it is difficult to tell. The symptoms at first were about equal, and the differences did not show themselves until towards the end. There was next a recovery of seven cases in succession; in these the remedy was administered less frequently, but subsequently two deaths occurred under the less frequent administration. The chloroform was administered also by inhalation, in some of the more severe cases of cramps, with the effect of affording relief in every instance. The inhalation was not carried so far as to produce insensibility. Although I am still of the opinion that chloroform properly regulated is the remedy of all others hitherto tried to be depended on, yet it cannot be considered a specific for cholera."