Barium: A Cause of the Loco-Weed DiseaseCrawford, Albert C. (Albert Cornelius)
Science
Barium: A Cause of the Loco-Weed Disease
Crawford, Albert C. (Albert Cornelius)
Astragalus earlei; Barium
_Experiment No. 7._--On February 19, 1906, a white and brown rabbit
whose temperature was 103.2°F. was fed 30 c.c. of aqueous fluid
representing the concentrated extract of 125 grams of the fresh
_Astragalus mollissimus_, collected September, 1905, and preserved with
chloroform. The rabbit weighed 1,502.5 grams. This extract was fed at
1.45 p.m., and at 4.15 p.m. the temperature was 102.6°F., but there
were no marked symptoms. The following day at 2.04 p.m. the temperature
registered 102.5°F. The same amount of extract was given at 2.09 p.m.
The temperature at 4 p.m. was 99.8°F., the animal was dull, and the
pupils were perhaps a little smaller. The animal could not be turned
over without resistance. The following day, February 21, at 1.30 p.m.
the temperature was 102.6°F., and at 1.45 the same amount of extract
was given. At 1.54 p.m. the animal was much duller and the breathing
was very rapid. At 4.10 p.m. the temperature was 101.3°F. The animal
had been dull ever since the feeding was begun. It nibbled food shortly
before the last feeding. On February 23 the same amount of extract was
given at 2.16 p.m., temperature 99°F. The breathing was very rapid,
the ears shaking, and there was a sleepy, dull look about the animal. At
3.30 p.m. the animal was dull, but would still walk about if disturbed.
At this time the animal weighed 1,445.8 grams. At 4.30 p.m. the
temperature was 102°F. and the pupils were about normal size. There was
a marked sleepy look about the animal, which sat quietly in its cage.
February 24, at 1 p.m., the animal was very dull and could with ease be
turned on its back with its feet in the air. It would sit in its cage
perfectly quiet. The weight at this time was 1,417.5 grams, the
temperature 96.6°F. On February 26 the animal weighed 1,360.8 grams. It
was dull and refused to eat. The abdomen felt very distended and
tympanitic. February 27 the weight was still 1,360.8 grams, and the
animal sat in its cage as if asleep, with eyes half closed. There was no
diarrhea and the abdomen was very distended. At 11.15 a.m. there was a
general convulsion and the animal fell over. At 12 m. the abdomen seemed
even more swollen, the animal was hardly able to walk, and it fell over,
uttering a cry. Pupils were about normal--perhaps a little smaller. The
animal died at 12.10 p.m.
Public-domain text, read in full here on John Shaqi.
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