Barium: A Cause of the Loco-Weed DiseaseCrawford, Albert C. (Albert Cornelius)
Science
Barium: A Cause of the Loco-Weed Disease
Crawford, Albert C. (Albert Cornelius)
Astragalus earlei; Barium
_Experiment No. 8._--On February 18, 1906, at 2 p.m., a rabbit whose
temperature was 102.2°F. was fed with the aqueous extract of 125 grams
of fresh _Astragalus mollissimus_, collected in September, 1905, and
preserved in chloroform, 30 c.c. of the fluid being used. At 4.25 p.m.
the temperature was 102.4°F. No symptoms were noted. This rabbit
weighed 1,644.3 grams. On February 20 at 2.09 p.m. the temperature was
102.2°F. and the rabbit showed no symptoms. The same dose was repeated
at 2.15 p.m. At 4 p.m. the temperature was 100.3°F. The rabbit was
dull but could not be turned over without a struggle. February 21 at
1.30 p.m. the temperature was 101.4°F. The same amount of extract was
fed at 1.45 p.m. At this time the animal was dull and breathed more
rapidly. At 4.10 p.m. the temperature was 97.3°F. Next day the same
amount of extract was again given at 2 p.m. At 2.16 p.m. the breathing
became rapid and the animal duller. The ears were directed forward. At
4.15 p.m. the temperature was 101.6°F.; weight 1,757.7 grams; animal
slightly dull. February 24, temperature 102°F., weight 1,786 grams.
March 5, weight 1,729.3 grams. The animal was fed at 3.20 p.m. with a
concentrated extract of 125 grams of _Astragalus mollissimus_, collected
in September. Temperature at time of feeding 100.4°F.; 3.40 p.m., no
symptoms; 4 p.m., temperature 102°F. March 7, weight 1,644.3 grams;
March 8, weight 1,672.6 grams; March 10, weight 1,701 grams; March 12,
weight 1,658.4 grams; March 14, weight 1,701 grams.
In this case, where the same dose was given in a period of five days,
very little effect on the rabbit was noted.
_Experiment No. 9._--On March 1, 1906, a black rabbit weighing 2,664.8
grams was fed with a concentrated aqueous extract of 250 grams of fresh
_Astragalus mollissimus_, collected in the fall of 1905.
Public-domain text, read in full here on John Shaqi.
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