The question of the influence of occupation along other lines is really more interesting, because more obscure; but a careful study of available data tends to show the correctness of the thesis on which my former lectures and these are based. This, as you know, is that our so-called advancing civilization, with all its errors of life, in many directions, is at the bottom of the steady increase in the mortality from cancer. One of the most interesting contributions to this was the investigation made by Dr. Latham, Registrar-General, in a study of cancer returns in England; this showed that the mortality from the disease was more than twice as great among well-to-do men having no specific occupation as among occupied males in general, the respective mortality ratio being 96 for the former and only 44 for the latter. The same observation has been made elsewhere. Moreover, it is reported from several reliable sources that the death rate from cancer in many cities is proportionately greater among the rich and those in easy circumstances than among the poor, wage-earning element of society. This would seem to show that occupation in general acts favorably against the development of cancer. This fact is quite understandable when we consider that those engaged in active work are less liable to suffer from the effects of gluttony and indolence, with their concurrent metabolic disturbances, than the well-to-do with ease and luxurious habits. It is remarkable, however, that in asylums, homes for the aged, prisons, convents, monasteries, etc., where the inmates are relatively unoccupied, many writers confirm the fact that cancer is very seldom seen; but this again is explained by the simple and frugal diet enforced, with very little meat, which agrees with our thesis. Statistics from life insurance companies show that cancer is decidedly more common among persons of over-weight than among under-weights. In regard to the occupations of those dying from cancer it is interesting to note that standing among the highest per 100,000 population, in English statistics, come brewers, inn-keepers, and butchers, whose metabolism can be greatly disturbed by alcohol and meat; also indoor servants are more apt to be affected, while those of more or less sedentary occupation, such as school teachers, clergymen, physicians, and tailors, likewise stand very high on several lists. On the other hand, those engaged in active physical exercise, such as miners, farm laborers, carpenters, blacksmith, mail-carriers, and others, are among those least frequently attacked.