the serum-agar mixture in several cases. Cultures were obtained in broth
and in milk without coagulation, contrary to the statement of Preisz. No
gas was produced in sugar broth. Nowak inoculated a number of pregnant
laboratory animals, and produced abortion with great regularity in
guinea pigs and rabbits by subcutaneous, intravenous and intraperitoneal
injection. He did not succeed in producing abortion by intravaginal
application nor by feeding. No tests were made upon larger animals much
to his regret, as in his opinion the experiments of Bang upon cows still
left something to be desired in the way of experimental evidence.
McFadyean and Stockman (1909) have investigated the contagious abortion
of cattle in Great Britain, and have found it to be identical with that
studied by Bang in Denmark. They were able to produce the disease in
cows by intravenous injection of natural virus and of active pure
cultures, without a failure in eight experiments. By intravaginal
application they caused the disease twice with cultures and three times
with natural virus, but also failed to obtain any result in three trials
with the natural virus. Subcutaneous inoculation was successful three
times in five trials. By feeding they produced the disease three times
in four trials. These authors consider ingestion to be an important mode
of contracting contagious abortion in nature.
Zwick (1910) has made a preliminary report of the bacteriological
investigation of contagious abortion at the German Imperial Health
Office. By a comparative study of cultures, the unity of the disease in
Denmark, Germany, England, and Holland has been established. Certain
individual differences were detected in the various culture strains
examined, and it was found that the bacillus could be readily cultivated
upon various ordinary laboratory media, and that it could also adapt
itself to an aerobic existence, thus confirming the work of Nowak. In
one instance the bacillus grew aerobically immediately upon isolation
from the animal body. Abortion was induced in sheep, goats, and rabbits
by intravenous injection, intravaginal application, and also by feeding.
Work upon the use of abortin (analogous to tuberculin) for diagnosis,
and upon the agglutination and complement fixation tests, was in
progress at the time the report was made.
BACTERIOLOGICAL OBSERVATIONS AND EXPERIMENTS AT THIS STATION
Public-domain text, read in full here on John Shaqi.
Reviews
Reviews
No reviews yet
Be the first to share your thoughts on this work.
Join the Discussion
Join the discussion
Sign in to leave a comment or review.
Sign InorCreate an account