Arthur R. Graham, M.D., etc., of Weybridge, England, sends me the following interesting and conclusive case: “No deaths; but one alarming accident worth recording: I had injected a large dose (probably three-quarters of a grain) into the _right_ forearm of a woman whom I was in the habit of injecting daily. Almost immediately she started up, and holding up her _left_ hand and looking at it, exclaimed, ‘O, how funny my fingers feel!’ and fell back in a dead faint, with blanched lips. I immediately bound a tape tightly around the arm, above the puncture, and then gave brandy and asafœtida injections, but she remained unconscious, I think, for more than half an hour. After she was sufficiently recovered to talk rationally I loosened the tape, when she immediately fainted again. Of course, I at once tightened the ligature and kept it so for some hours. The second swoon was less alarming than the first. In the first no pulse could be felt, nor could the heart sounds be heard, excepting with great difficulty. My impression at that time was that, had I not applied the ligature at once I should have had a fatal result to chronicle. It was the impulse of the moment to tie on the tape, and had I had time to reason I should have rejected the idea as an entirely useless one; but in any similar emergency I should now recommend any one to try it.” Dr. E. Fletcher Ingalls[13], who has devoted much attention to the hypodermic injection of morphia, reports the following case: “I have often used hypodermic injections of morphia, and always with good results, until a few weeks since, when I obtained alarming results from the administration, by this method, of one-fourth of a grain of morphia. “The patient, in consequence of continuous watching with sick children, had become debilitated, and, as a result, suffered at times from severe pains of a neuralgic character. I was called in the night to see her in one of these attacks. The pain had commenced about twelve hours previously, and with frequent exacerbations, had steadily increased in severity until it had become unbearable. “I dissolved one-fourth of a grain of morphia in pure water, and administered it under the integument on the outer side of the arm. Within a few seconds the breathing became stertorous, the pulse failed, the lips and countenance became livid, and the eyes were set; respiration ceased, the radial and cardiac pulsations were lost, and the heart sounds could not be distinguished. The woman was to all appearances dead. How long this condition continued I cannot tell; it seemed an age, but was probably only ten or fifteen seconds, for by prompt means I succeeded in resuscitating my patient.