As explained above, when the nerve supplying a muscle is diseased it no longer responds to the faradic current. On further testing this with the galvanic or continuous current it responds, but the contraction is not brisk but begins slowly and relaxes slowly, though the contraction as a whole may be larger than that of a normal muscle. This excessive contraction is known as hyperexcitability to galvanism. This form of contraction is that obtained when the muscle fibre itself is stimulated. Again, whereas in normal muscle KCC > ACC, when the nerve is degenerated KCC = ACC or ACC > KCC. Also in the more severe forms of nerve injury tetanic contractions may be set up in the paralysed muscles, by closure of the current either at the anode or kathode. These charges are known as the reaction of degeneration or RD, and are of great value in diagnosis. They occur only after sudden or acute damage to the nerve cells of the anterior horn of the spinal cord, or to the motor nerve fibres proceeding from these cells. Thus RD is present in infantile paralysis, acute neuritis, &c., but absent in progressive muscular atrophy where the wasting of nerve and muscle takes place extremely slowly. The reaction of degeneration in the nerve is shown by disappearance of reaction to either kind of current, preceded for some days by hyperexcitability to either current. Where the muscle wasting is due to a lesion in the muscle alone, as in ischaemic myositis (usually due to injury from tight bandaging or badly applied splints), no reaction of degeneration is found; the only change is a loss of power in the contraction. If the damage to the anterior horn cells be only very slight, there may only be partial RD, and the prognosis is given according to the extent of RD. From this account it is clear that the greatest value of the continuous current lies in its use in diagnosis. But it is also applied extremely successfully, in combination with massage, to cases of infantile paralysis. Wrist drop from lead poisoning and lead neuritis of all kinds, reflex muscular atrophy and the muscular wasting of hemiplegia, are all benefited by the continuous current; the severe pain of sciatica, and the inflammation of the nerve sheath in these cases, can be arrested more quickly by galvanic treatment than in any other way. Nearly all forms of neuritis, both of the cranial and other nerves, are best treated by the continuous current. The action in all cases is to stimulate the natural tendency to repair, very largely by improving the circulation through the injured parts.