Coindet says, that he has seen several cases of bronchocele, complicated with watery cysts, yield completely to the action of iodine. I have only had occasion to see one such case treated by this medicine. It was somewhat lessened in its bulk, and the patient was certainly relieved, but the disease was by no means cured. If the iodine be given internally, it is indispensably necessary to watch its effects from day to day. No peculiarity of circumstances whatever can dispense the physician from this care; and if it be recollected that it is yet a new medicine, that unknown accidents, to which it is liable, may be discovered by future investigations, this caution will not appear superfluous. The case related by Dr. Coindet, to which we have already alluded at page 36, in which a very powerful and painful effect was produced at the end of the fifth day, sufficiently evinces the necessity of the watchfulness here recommended. When iodine acts kindly on the constitution, no other effect will be found to accompany its use, but a diminution of the tumor and a little nervous excitement, which is sometimes not so severe as to become disagreeable. The increase of appetite is a very frequent effect of iodine, and it is sometimes very troublesome, because it is extremely necessary not to indulge it. The diet of the patient should be good, but by no means full, which the occasional voraciousness of his appetite would lead him to adopt. * * * * * Having established that the use of iodine in bronchocele was owing to its effect on the absorbent system, it was natural to conclude that it would be of equal service in the cure of scrophula.[8] Accordingly, we find that Dr. Coindet made trial of it in the cure of the latter disease, soon after he had determined its virtues in the former, and that his experiment was followed by the most satisfactory result. I have already considered at so great length the general effects of iodine on the constitution, that little remains for me in this place but to mention the particular cases in which I have found it useful, and those in which it has failed my expectations. [8] On perusing most of our practical, and more especially our systematic authors, this term will be found of such latitude and various meaning, that, were they indiscriminately followed, scrophula might be considered an universal disease. In this place, we confine our attention to those diseases which are familiar to all practitioners, scrophulous tumors of the conglobate glands.