The construction of the single microscope is so simple, that it is susceptible of but little improvement, and has therefore undergone but few alterations; and these have been chiefly confined to the mode of mounting it, or the additions to its apparatus. The greatest improvement this instrument has received, was made by Dr. Lieberkühn, about the year 1740; it consisted in placing the small lens in the center of a highly polished concave speculum of silver, by which means he was enabled to reflect a strong light upon the upper surface of an object, and thus examine it with great ease and pleasure. Before this contrivance, it was almost impossible to examine small opake objects with any degree of exactness and satisfaction; for the dark side of the object being next the eye, and also overshadowed by the proximity of the instrument, its appearance was necessarily obscure and indistinct. Dr. Lieberkühn adapted a microscope to every object; it consisted of a short brass tube, at the eye end of which a concave silver speculum was fixed, and in the center of the speculum a magnifying lens: the object was placed in the middle of the tube, and had a small adjustment to regulate it to the focus; at the other end of the tube there was a plano convex lens, to condense and render more uniform the light which was reflected from the mirror. But all these pains were not bestowed upon trifling objects; his were generally the most curious anatomical preparations, a few of which, with their microscopes, are, I believe, deposited in the British Museum. It will be proper, in this place, to give some account of Mr. Leeuwenhoek’s microscopes, which were rendered famous throughout all Europe, on account of the numerous discoveries he had made with them, as well as from his afterwards bequeathing a part of them to the Royal Society. The microscopes he used were all single, and fitted up in a convenient simple manner; each of them consisted of a very small double convex lens, let into a socket between two plates rivetted together, and pierced with a small hole; the object was placed on a silver point or needle, which, by means of screws adapted for that purpose, might be turned about, raised or depressed at pleasure, and thus be brought nearer to, or be removed farther from the glass, as the eye of the observer, the nature of the object, and the convenient examination of its parts required. Mr. Leeuwenhoek fixed his objects, if they were solid, to the foregoing point with glue; if they were fluid, he fitted them on a little plate of talc, or exceeding thin blown glass, which he afterwards glued to the needle, in the same manner as his other objects. The glasses were all exceeding clear, and of different magnifying powers, which were proportioned to the nature of the object, and the parts designed to be examined. But none of those, which were presented to the Royal Society, magnify so much as the glass globules, which have been used in other microscopes.