The whole skin is never at the same time paralyzed; there is rarely even hemiplegia in this respect; the feeling is not extinguished but in an insulated part. I would remark that the existence of these paralyses is also a proof of the want of nervous influence upon cutaneous exhalation and the capillary circulation, since both go on very well in this case as well as in paralysis of motion, as I have observed above. Cut the nerves of a limb of an animal, in order to render this limb insensible; if after this you apply an irritant, the skin will inflame as usual. When the animal sensibility is in exercise, is there a kind of erection of the papillæ that they may feel more acutely? The same observation may here be made as was in regard to the mucous surfaces. This erection is an ingenious idea of some physicians, and not a fact which rests upon observation. I even think that this contradicts it; for examined with a glass the papillæ appear to be constantly in the same state. Why should not the skin feel like a nerve laid bare, like the eye, the ear, &c. in which these sorts of erections have never been imagined? Animal contractility is wholly foreign to the cutaneous organ, which moves voluntarily only by the influence of its fleshy pannicle. _Properties of Organic Life._ Organic sensibility and insensible contractility exist in the highest degree in the cutaneous organ. The external capillary system, which forms the reticular body, is, as I have said, especially the seat of these properties. They are in constant activity in order to preside, 1st, over the capillary circulation; 2d, over exhalation; 3d, over absorption; 4th, over the nutrition of the whole dermoid texture; 5th, over the secretion of the cutaneous oil, if the sebaceous glands exist. It is not astonishing that these properties should be so much developed in the skin, in which they have so many functions to support. Add to these considerations the constant action of external bodies, an action which keeps this organ in continual excitement, which incessantly stimulates its sensibility, which is to this sensibility what that of the bodies contained in the mucous surfaces is to the sensibility of these surfaces; the irritation is even more sensible, because the stimuli are oftener changed. A thousand agents of nature, of different density and composition continually succeed each other on the exterior of the body, and at the same time that they act upon the animal sensibility of the skin, to produce various sensations, they excite the organic sensibility in order to support the functions over which this sensibility presides. Is it astonishing then that the greater number of cutaneous diseases supposes an alteration in this property and in the insensible organic contractility which is not separated from it? I divide these diseases into four classes, according to the structure we have distinguished in the skin.