This beautiful manuscript, which was executed in Constantinople, contains five large and elaborate miniatures, and a great number of vignettes representing varieties of plants. The fifth of the large miniatures consists of a central group framed by two squares interlaced within a circle. The plait pattern on the bands which form the framework, and the whole design closely resemble a fine mosaic pavement of the second century A.D. The resemblance is far too close to be accidental; and indeed this manuscript is not the only example we have of miniature painters copying patterns and motives from mosaic floors of earlier date. _Portrait figure._ The central group in this beautiful full page painting represents Juliana Anicia, for whom the manuscript was written, enthroned between standing allegorical female figures. Minutely painted figures of Cupids, engaged in a variety of handicrafts and arts, fill up the small spaces in the framework. _Inferior paintings._ In these paintings we have a curious combination of different styles; the enthroned figure of the Princess is of the stiff Byzantine style, while the attendant figures and the little Cupids are almost purely classical in drawing. This manuscript forms a link between the classical or Graeco-Roman and the Christian or Byzantine style. Other paintings in the same manuscript are very inferior in design, partaking of the late Roman decadence, rather than of the better and earlier art of the above mentioned picture. Fig. 7 shows one of these. It represents Dioscorides seated on a sort of throne; in front is a female figure _Euresis_ (_Discovery_) presenting to him the magic plant _mandragora_ (mandrake). The dying dog refers to the popular belief, given by Josephus, as to the manner in which the mandrake was gathered. When plucked from the ground the mandrake uttered a scream which caused the death of any living creature that heard it; it was therefore usual to tie a dog to the plant and retire to a safe distance before calling it, and so causing the dog to drag the plant out of the ground. On hearing the scream the dog dropped down dead. Cf. Shaks., _Romeo and Juliet_, IV. iii. [Illustration: Fig. 7. Miniature from the manuscript of the work on _Botany_ by Dioscorides, executed in Constantinople about 500 A.D.] _Colours and gold._ The colours used in the _Dioscorides_ of Juliana are very brilliant, especially the gorgeous ultramarine blue, and are glossy in surface owing to the copious use of a gum medium. Gold is very largely and skilfully used, especially to light up and emphasize the chief folds of the drapery, a method which is very widely used in Byzantine art, both in the colossal pictures of the wall-mosaics, and also in most of the finest class of illuminated manuscripts. _Cloisonné enamel._