On Tiaropsis indicans this poison has the effect of causing a general spasm, which would be undistinguishable from that which in this species results from general stimulation of any kind, were it not that there is a marked difference in one particular. For in the case of strychnia poisoning, the spasm, while it lasts, is not of uniform intensity over all parts of the nectocalyx; but now one part and now another part or parts are in a state of stronger contraction than other parts, so that, as a general consequence, the outline of the nectocalyx is continually changing its form. Moreover, in addition to these comparatively slow movements, there is a continual twitching observable throughout all parts of the nectocalyx. Each individual twitch only extends over a small area of the contractile tissue; but in their sum their effect is to throw the entire organ into a sort of shivering convulsion, which is superimposed on the general spasm. After a time the latter somewhat relaxes, leaving the former still in operation, which, moreover, now assumes a paroxysmal nature--the convulsions consisting of strong shudders and frequent spasms with occasional intervals of repose. In the case of Tiaropsis diademata the action of strychnia is very similar, with the exception that there is no _continuous_ spasm, although _occasional_ ones occur amid the twitching convulsions. After a time, however, all convulsions cease, and the animal remains quiescent. While in this condition its reflex excitability is abnormally increased, as shown by the fact that even a gentle touch will bring on, not merely a single responsive spasm, as in the unpoisoned animal, but a whole series of successive spasms, which are often followed by a paroxysm of twitching convulsions. The condition of exalted reflex irritability is thus exceedingly well marked. Recovery in normal water at this stage is rapid, the motions being at first characterized by a want of co-ordination, which, however, soon passes off.