Of the numerous but much smaller occurrences of lead elsewhere in Missouri and the Mississippi valley, none resembles this district in character, a fact which is unique. For while the Mechernich lead deposits, in Germany, are disseminated, and of even lower grade than in Missouri, they occur in a sandstone, and (like all the lead deposits outside of the Mississippi valley) they are argentiferous, at least to an extent sufficient to make the extraction of the silver profitable; and on the non-argentiferous character of the disseminated deposits hangs my story. Of the numerous hypotheses advanced to account for the origin of these deposits, there are only two that seem worthy of consideration: (a) the _lateral secretion theory_, and (b) _deposition from solutions of deep-seated origin_. Other theories evolved in the pioneer period of economic geology are interesting, chiefly by reason of the difficulties under which the early strugglers after geological knowledge blazed the pathway for modern research and observation. The lateral secretion theory, as now modernized into the secondary enrichment hypothesis, has much merit when applied to the southeastern and central Missouri lead deposits. For the limestones throughout Missouri—and they are the outcropping formation over more than half of the State—are rarely, if ever, devoid of at least slight amounts of lead and zinc, although they range in age from the Carboniferous down to the Cambrian. The sub-Carboniferous formation is almost entirely made up of limestones, which aggregate 1200 to 1500 ft. in thickness. They frequently contain enough lead (and less often zinc) to arouse the hopes of the farmer, and more or less prospecting has been carried on from Hannibal to St. Louis, or 125 miles along the Mississippi front, and west to the central part of the State, but with most discouraging results.