Nestorias, patriarch of Constantinople in 428, had begun by persecuting the Arians; but while he insisted that in Jesus were combined two persons and two natures, he insisted that the Virgin Mary was the mother of Christ considered as _man_, but not the mother of Christ considered as _God_; and that, consequently, all those who gave her the title of _Dei Genitrix_, _Deipara_,[1] were in error. There were many who adopted these opinions, but by a large portion of the Church they were repudiated with horror, as utterly subverting the doctrine of the mystery of the Incarnation. Cyril of Alexandria opposed Nestorius and his followers, and defended with zealous enthusiasm the claims of the Virgin to all the reverence and worship due to her; for, as he argued, the two natures being one and indivisible from the moment of the miraculous conception, it followed that Mary did indeed bring forth God,--was, in fact, the mother of God; and, all who took away from her this dignity and title were in error, and to be condemned as heretics. [Footnote 1: The inscription on the Greek and Byzantine pictures is actually [Greek: MAeR ThU] ([Greek: Mhaetaer Theos]).] I hope I shall not be considered irreverent in thus plainly and simply stating the grounds of this celebrated schism, with reference to its influence on Art; an influence incalculable, not only at the time, but ever since that time; of which the manifold results, traced from century to century down to the present hour, would remain quite unintelligible, unless we clearly understood the origin and the issue of the controversy. Cyril, who was as enthusiastic and indomitable as Nestorius, and had the advantage of taking the positive against the negative side of the question, anathematized the doctrines of his opponent, in a synod held at Alexandria in 430, to which Pope Celestine II gave the sanction of his authority. The emperor Theodosius II then called a general council at Ephesus in 431, before which Nestorius refused to appear, and was deposed from his dignity of patriarch by the suffrages of 200 bishops. But this did not put an end to the controversy; the streets of Ephesus were disturbed by the brawls and the pavement of the cathedral was literally stained with the blood of the contending parties Theodosius arrested both the patriarchs; but after the lapse of only a few days, Cyril triumphed over his adversary: with him triumphed the cause of the Virgin. Nestorius was deposed and exiled; his writings condemned to the flames; but still the opinions he had advocated were adopted by numbers, who were regarded as heretics by those who called themselves "the Catholic Church."