This leprous affection of the glands is macroscopically very readily recognisable. The glands are swollen as a whole, without any alteration in their form. On section, one sees the ampullæ and the medullary cords of a yellow or yellowish brown colour; this colour gives to the glands such a characteristic aspect that they can hardly be mistaken. The affection is best studied on the inguinal glands, and the retro-peritoneal ones in connection with them. The lowest inguinal gland is always most swollen, reaching sometimes to the size of a pigeon’s egg; the ampullæ and trabeculæ are coloured throughout a deep yellow; but the somewhat thickened capsule and the connective tissue framework have retained their greyish semi-transparent appearance, so that the structure of the gland stands out very clearly, especially if the lymph sinuses are injected with blood pigment, which is sometimes the case when there have been peripheral hæmorrhages in the nodules. As we advance upwards the glands are gradually less swollen, and the yellow colouring of the ampullæ and trabeculæ less intense, and one can further follow in the retro-peritoneal glands a gradual diminution of the affection until, about the level of the kidney or rather higher, normal glands are once more met with. The glands are permeable, but penetration is evidently more difficult, for the lymph vessels leading to them are dilated, especially those of the lowest and most swollen glands. With great patience and moderate pressure one can succeed in artificially injecting the lymphatics without causing extravasation. It may even be the case that only one, or at most one or two ampullæ are affected. Microscopically the ampullæ and trabeculæ are found more or less filled with brown bodies or globi. These are evidently lymph cells which have become filled with bacilli and their degenerative products--granules. One could hardly have a better demonstration of the functions of the lymphatic glands, as filters, than in these leprous glands. The circulation through them is not arrested; nevertheless, the glands retain the infectious product, and if it pass one gland it is arrested and retained in the next. Sometimes the quantity of this infection is so small that one or two ampullæ are sufficient to retain the whole of it. This indicates that the circulation in the gland does not take place exclusively through the lymph sinuses, but that the lymph reaching the gland must at once enter the ampullæ. A similar process is seen in tubercular lymphatic glands, in which one often finds only one or one or two ampullæ infiltrated with tubercle.