Medical Jurisprudence, Volume 2 (of 3)Paris, John Ayrton
Science
Medical Jurisprudence, Volume 2 (of 3)
Paris, John Ayrton
Medical laws and legislation -- Great Britain
After the view which we have taken of the operation of this salt in
large doses, it necessarily follows that copious dilution is the very
first object which we have to accomplish, and then the ejection of the
fluid by vomiting. _Sydenham_ relates an interesting case of poisoning
by this substance, which was successfully treated by copious draughts of
water, and repeated vomiting.[276] But it becomes a question of great
practical importance to enquire, whether there may not exist some
counterpoison or antidote which, by decomposing the salt, will at once
disarm it of its virulence? This question has been investigated in a
very masterly style by _Orfila_, who has clearly proved by experiment,
that neither the _alkaline salts_ and _earths, the sulphurets of potass
and of lime_, nor the _martial alkaline tinctures_, as proposed by
_Navier_,[277] deserve the least confidence; for although the salt may
by some of these bodies be decomposed, yet the resulting oxide will
prove as virulent as the original compound; equally inefficient are the
other substances which have been proposed as counter-poisons, such as
_sulphuretted hydrogen_, _solutions of sugar_,[278] _the infusions of
Peruvian bark_,[279] and _metallic mercury_.[280]
_M. Orfila_ having observed the facility with which _albumen_ decomposes
corrosive sublimate, and gives rise to a triple compound of albumen,
muriatic acid, and protoxide of mercury, induced him to ascertain by
experiments whether the _white of eggs_ might not prove an antidote to
that poison; the result of his inquiry has shewn that this is the case;
and that by mixing such albuminous matter, in _large quantities_, with
the diluents given to provoke vomiting, the happiest effects may be
anticipated. Many examples are recorded of the success of this practice.
In the Transactions of the King and Queen’s College of Physicians in
Ireland, an interesting case of this kind is related by _Dr. Lendrick_;
it is, however, but justice to state, that there are instances also of
the failure of this antidote. In the 41st volume of the _London Medical
and Physical Journal_, p. 204, the reader will find the case of a girl
who was poisoned by a drachm of sublimate, and who, notwithstanding the
copious administration of albumen, died in ninety hours afterwards.
Public-domain text, read in full here on John Shaqi.
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