This was the same affection that attacked our colonies in Canada, but at that time we had no knowledge of the therapeutic indications in such emergencies, and quote as a proof of this a remarkable observation inscribed on the registers of Cartier on his vessels during his sojourn in Canada: “The disease commenced in our midst in a curious and unknown manner; some patients lost their flesh and their limbs grew black and swollen like charcoal, and some were covered over with bloody splotches like purpura; after which the disease showed itself on the hips, thighs, arms, and neck, and in all the mouth was infected and rotten at the gums, so that all the flesh fell off to the roots of the teeth, which also most often dropped out; and so terrible was this plague that on my three ships by February only ten healthy men were about out of a crew of over a hundred. “And, as the disease was unknown to us, the Captain of the ships was asked to open a few bodies to see if we could possibly detect the lesion and thus be able to protect the survivors. We found the hearts of the dead to be white and withered, surrounded by a rose colored effusion; the liver healthy, but the lung black and mortified and all its blood retired to the sac of the heart. The spleen likewise was impaired for about two finger-lengths as though rubbed by a rough stone.” From this autopsy rudely made[26] it is true we discern most of the signs of scrofula; a profound alteration of the blood and an effusion of the liquids into certain viscera, denoting a diminution in the amount of fibrin and the number of globules, alterations that also serve to explain the tendency to hemorrhages observed in very serious cases of scurvy. LEPROSY. Leprosy is a disease originating in the Orient; Egypt and Judea were formerly the principal infected centers. It was the return of an expedition to Palestine, under Pompey, that imported the malady to Italy. In the first years of the Christian Era it is mentioned by Celsus, who advised that it should be treated by sweating, aided by vapor baths. Some years later Areteus used hellebore, sulphur baths, and the flesh of vipers taken as food, a treatment adopted by others, as, for instance, Musa and Archigenes. In the second century the disease was in Gaul; Soranus treated the lepers of Aquitaine, who were numerous.[27] According to Velly, leprosy was common in France in the middle of the eighth century epoch, when Nicholas, Abbot of Corbeil, constructed a leper hospital, which was never much frequented until after the Crusades of the eleventh and fourteenth centuries. At this period the number of lepers, or _ladres_, a name given to the unfortunates in remembrance of their patron saint, St. Lazarus, became so great that every town and village was obliged to build a leper house in order to isolate the afflicted. Under Louis VIII. there were 2,000 of these hospitals; later the number of such asylums reached 19,000.