For the next three centuries Councils and Bishops struggled manfully to put into force the Bull _Periculoso_, but without success; the constant repetition of the order that nuns should not leave their convents is the measure of its failure. In the various reformed orders, which were founded in the fifteenth and sixteenth centuries, the insistence upon enclosure bears witness to the importance which was attached to it as a vital condition of reform: Boniface IX's ordinances for the Dominicans (1402), St Francis of Paula's rule for his order in Calabria (1435), the rule of the Order of the Annunciation, founded by Jeanne, daughter of Louis XI, at the close of the fifteenth century, Johann Busch's reforms in Saxony, the reformed rules given by Etienne Poncher, Bishop of Paris, to the nuns of Chelles, Montmartre and Malnoue (1506) and by Geoffrey de Saint Belin, Bishop of Poitiers, to the nuns of the Holy Cross, Poitiers (1511), all insist upon strict enclosure[1078]. Similarly a long list might be drawn up of general and provincial councils and synods which repeated the ordinance, culminating in the great general Council of Trent, which renewed the decree _Periculoso_ and was itself followed by another long series of provincial councils, which endeavoured to put its decree into force. But these efforts were still attended by very imperfect success, for the worldly nuns of the sixteenth and seventeenth centuries chafed at the irksome restriction no less than did their predecessors of the middle ages. When, in 1681, Jean-Baptiste Thiers published his treatise on the enclosure of nuns he announced his reason to be that no point of ecclesiastical discipline was in his day more completely neglected and ignored[1079].