to by Sydenham, Baillarger, Westphal, Greenfield, Gubler and many others. Delasiauve very elaborately described the psychoses associated with typhoid fever in 1849. The mental disorders accompanying gout were discussed at considerable length by Sydenham and were referred to as early as 1699 by Philander Misaurus. According to Bucknill and Tuke[261], Misaurus made the following very interesting suggestions in an article entitled "The Honour of the Gout": "It would be worth inquiry, whether the gout is not as effectual against madness; and we may reasonably believe that it is so, if upon examination, it should be found that there are no gouty people in Bedlam; and then for the recovery of these poor creatures to their wits again, it will not need much consideration, whether they ought not to be excused the hard blows which their barbarous keepers deal them, and the Therapeutic method of Purging, Bleeding, Cupping, Fluxing, Vomiting, Clystering, Juleps, Apozemes, Powders, Confections, Epithemes, Cataplasms, with which the more barbarous Doctors torment them, and instead of their learned Torture, indulged for a time only, a little intemperance as to wine, or women, or so; or the scholar's delight of feeding worthily, and sleeping heartily, whereby they might get the Gout, and then their madness were cured." Clouston described a very definite form of phthisical insanity. Van der Kolk made the surprising statement that phthisis and mania often alternated in regular cycles. Nasse classified the mental conditions associated with fevers as either resulting directly from the febrile disturbance, constituting a prolongation of the delirium after the temperature subsided, or developing during convalescence.