A far more formidable occasional complication of neuralgia is inflammation affecting the eye. Mr. Jonathan Hutchinson records several cases in which neuralgic herpes zoster of the face was attended with iritis, with serious or even irremediable damage to the organ. For my own part, I have witnessed several instances in which neuralgia of the first and second divisions of the fifth has been attended with skin-inflammation, but only in one of these (just alluded to) did the inflammation present the characteristic appearances of herpes: in all the rest it far more closely resembled erysipelas. The skin was excessively reddened in an almost or quite continuous patch over the whole territory through which ran the painful nerves; by no means only linearly in the course of the nerves, though accurately limited to the district of the first or first and second divisions of the fifth. In the first case I saw (a woman, aged thirty-two), nothing could be more startling than the rapidity with which an irregular patch of the skin, including half of one cheek, the side of the nose, and a large part of the forehead and scalp on the same side, became converted into the dense, fiery-red, brawny tissue, with minute vesicles scattered over its surface, which looks so characteristic of erysipelas; this commenced immediately on the subsidence of severe neuralgic pain. During the erysipelatoid inflammation, though there was no spontaneous pain, the neuralgia could be instantly lighted up for a moment by pressure on the infra-orbital foramen, on the supra-orbital notch, or upon the malar bone, about its centre. Since that time I have seen several cases of a similar character; two of these, which were reported in the _Lancet_ for 1866, I shall here reproduce: [Extensive inquiries convinced me that the tendency to erysipelatous complication of facial neuralgia is exceedingly common. Eulenburg expressly confirms my original statement to this effect, and extends it to all neuralgias.]