St., 46 years old, contracted syphilis several years ago and was relieved of it by mercurial treatment and Zittman's decoction. About six years ago he felt out of sorts, and a papular eruption appeared on forehead, temples, and especially at the root of the nose. Though treatment was immediately instituted, still in a few weeks the face of the patient was covered by an ugly, foul-smelling crust. Cod-liver oil was now taken internally, and applied externally till the scuffs fell off and the eruption concentrated on three points. For six months that treatment was kept up, but after being omitted for a few weeks, the eruption spread again to its former extent. Every treatment was tried in rotation without the least benefit. In the spring 1856 he entered my clinic. In the centre of the forehead, at the root of the nose, on both eyebrows, on the temples and right cheek there are moist herpetic eruptions covered with crusts, exuding on least pressure an acrid ichor and easily bleeding. Around these eruptions the skin is injected, reddened, interspersed with a large network of veins. Cough and expectoration hint to a beginning of tuberculosis, an heirloom in the family. Little appetite, disturbed digestion, tardy defecation, and evening fever. He is ordered Solutio arsen. brom. twice a day, four drops in a glass of water, and already after two weeks the eruption begins to dry up, appetite returns, and bowels are regular. A generous diet and fresh meat several times a day are accessories to an arsenical cure. After two months two crusts fall off and the skin under them is soft, shining, somewhat red. About July all eruption had gone, and the cough greatly improved. A few months ago I saw the patient again, and I feel sure that the disease is eradicated.