SYMPTOMS.—There is a slight swelling of the limbs, most likely to be about the hocks. The swelling may disappear by exercising, but will soon return. The swellings present a very abrupt appearance, nearly the same as if a string were tied around the limbs and swell very quickly, and symptomatic of Purpura. Exudations take place in which, if on white limbs, you will see little red spots, from which a liquid is oozing. The swelling is very painful and the entire limb may be swollen. Small vesicles appear on the limbs and also in the mucous membranes, and it is well to look at the mucous membranes before giving your opinion, as you will, no doubt, detect these spots, which may extend into the lungs. These spots increase and may run into each other. The mucous membranes of the nose may become a mass of corrupt matter. The upper lip may hang pendulous, which is due to the want of nervous stimulus. If the nostrils are swollen very badly, there is difficulty in breathing and if the animal is not able to take food, the symptoms are considered very bad. The pulse varies much in some cases; although the swelling is very great, the pulse may not be more than forty or fifty per minute. The temperature is elevated one to three degrees above normal, there may be a cough and a brownish colored discharge from the nostrils. The mouth and eyes become affected and, together with the discharge from the nose, the horse is a loathsome looking object. In milder cases the appetite is retained, or the animal may take food one day and the next refuse it. The bowels are constipated as a general rule in the first stages of the disease and the urine may be of a dark color, may even contain blood. There may be a peculiar dropsical swelling of these petechial spots or it may show itself in connection with the eyes and there may be blood extravasation without outer symptoms. This disease may effect the bowels, liver, lungs, etc. The animal usually stands, perhaps from the difficulty in moving the limbs. It is necessary to watch the case closely, for flies will attack him and he will be filled with maggots. Sloughing may take place; the entire sheath or patches upon the body may slough off and there may be paralysis of the penis. TREATMENT.—Place the animal in a clean, light, comfortable stall. If the weather is cold, blanket. The following medicine is recommended because of its particular effect on the blood in this disease: Chlorate of Potash, eight ounces; Iodide of Potash, eight ounces; Quinine Sulphate, eight ounces. Make into thirty-two capsules and give one capsule every six hours. Also administer one ounce capsules filled with Spirits of Turpentine three or four times a day. Moisten the capsules with Sweet Oil and give with capsule gun. Feed hot bran mashes containing two or three ounces of pure Flaxseed meal. Also, feed vegetables, green grass, if possible. QUITTOR. (_Fistula of the Foot_)