A solution is made in the proportion of half or the whole of a grain, to half an ounce of simple or some lightly aromatic water, sweetened; and it is given every two hours. The patient is desired to drink very sparingly; for without this caution, the medicine would most probably produce too much of emetic effect. In the first instance, this result very commonly happens; but it is remarkable how soon the stomach accommodates itself to large doses of this active medicine. When its continued use produces sickness, syrup of white poppy is added, in the proportion of an ounce to half a pint of the antimonial solution; or, as an equivalent, a grain of extract of opium. The total quantity of the tartar emetic is very commonly increased to twenty grains and upwards in the twenty-four hours. I saw an elderly man, who had, in this space of time, on the preceding day, taken sixty grains without having experienced nausea, or any other inconvenience. M. Laennec considers that the tartar emetic, when administered with the freedom which I have described, exerts a highly useful power in diminishing inflammatory action in continued fever, and in the phlegmasiæ; and he is most satisfied with its action, when, after the first day or two, it ceases to produce any sensible effect on the stomach. Reflecting on the extraordinary circumstance of the exhibition of this active medicine in such immense quantity with seeming impunity, I thought it probable that the French preparation might be weaker than our own; but on comparing the crystals which I procured at Paris, with those prepared according to the London Pharmacopœia, I could not discover any difference; nor is there the least essential distinction in the mode of preparation, as directed by the London Pharmacopœia and the French codex. I have lately had many opportunities of prescribing tartar emetic on the principle of treatment which I have described; and I have been perfectly satisfied with its useful agency; but I have usually commenced with one grain, and never exceeded two grains, for the first twenty-four hours; nor found it necessary to go beyond eight in the progressive quantity; except in one case of insanity, in which sixteen grains were given daily for a short time, with the greatest advantage. In the quantity of two grains, it has usually produced considerable sickness for the first day or two; but afterwards, even the increased doses have seldom caused any nausea.