On the Continent some old records are obtainable. Thus, according to Grenser, of 14,466 infants born living at the Maternity at Dresden from 1816 to 1864 there were sixteen cases of simple harelip, and nine with fissures of the palate. Credé states that amongst 2044 infants examined at birth, only one case of simple harelip was observed, and one of complete division of the hard and soft palate. OCCURRENCE IN ANIMALS. These conditions obtain not only in the human subject, but also in animals, though not so commonly. Thus Sutton figures a right-sided harelip in a slink calf, and mentions a specimen of a harelip in a lamb in the museum of the Odontological Society; and in our museum at King’s College there is a specimen of a right-sided harelip in a kitten with a cleft alveolus, but the palate is intact. Cleft palate occurs more frequently in animals, particularly in those born in a state of captivity. Thus it appears that from statistics taken ten years ago 99 per cent. of the lion cubs born in the London Zoological Gardens had cleft palates, indicating that either the food-supply of these animals was not all that was requisite for perfect development, or that enforced confinement has a deleterious effect upon the multiplication of the species. It is a curious fact that in the Dublin Zoological Gardens the deformity was rarely noticed amongst the lion cubs, and the reason for this was supposed to be the supply of such food that the mother could eat both flesh and bone. Since the same practice has been followed in London, viz. giving the lions twice a week a young goat which they can eat, bones and all, the proportion of cleft palates in the young subsequently born has become considerably diminished. ASSOCIATION WITH OTHER DEFORMITIES. Occasionally, besides the fissured palate or lip, other deformities are noted in the same patient, but not so often as one might be led to expect. Mason records two or three cases as having come under his notice, the coincident deformities being respectively fistulous openings of buccal glands in an everted lower lip, congenital fissure of the lobe of the right ear, congenital talipes calcaneus and hypospadias. Dr. F. Warner records in the ‘Medical Times and Gazette,’ January, 1882, some cases of cleft palate associated with congenital defects of the heart and smallness of head, and also notes in his more recent report[7] that in 117 cases of malformations of the palate, other than cleft, only 42 were not in combination with other defects. Thus in 55 cases there were abnormalities in the shape of the cranium, in 16 cases defective development of the ear, in 12 the existence of an epicanthic fold, and in 15 cases other defects not tabulated.