On the origin of inflammation of the veins: and of the causes, consequences, and treatment of purulent depositsLee, Henry, M.D.
History
On the origin of inflammation of the veins: and of the causes, consequences, and treatment of purulent deposits
Lee, Henry, M.D.
Blood; Veins -- Diseases
Half an ounce of pus, similar to that used in the preceding instances,
but more putrid, in consequence of having been longer kept, was
introduced into the veins of a middling sized dog. The animal, as in
the other cases, was seized with vomiting, accompanied by violent
straining. Subsequently, strongly marked nervous symptoms made their
appearance. The eyes wandered; there was extreme sensibility, and
involuntary convulsive twitching over the whole body, accompanied by
faintness, hiccough, and short piteous cries. The walk was unsteady,
staggering, and without apparent object. There was furious delirium,
ardent thirst, dyspnoea, palpitation of the heart, etc. This
state lasted for nearly two hours, and the animal died in frightful
convulsions, without having experienced any critical evacuations, as in
the former cases.
_Post-mortem appearances._ On opening the body, while still warm, the
venous blood was found very firmly coagulated, not parting with any of
its serum when left at rest; the left ventricle of the heart showed, on
its external surface, some stains of the colour of lees of wine, formed
by a kind of concrete pellicle, which disappeared only after long
rubbing and maceration. The other organs appeared healthy.
EXPERIMENT XIII.
Some beef was allowed to decompose in some dog's blood; half an ounce
of the fluid resulting from the decomposition, was injected into the
jugular vein of a little bitch. Immediately, the animal made several
convulsive efforts to swallow, and soon became oppressed, uneasy, and
faint. At the expiration of an hour, there was great prostration,
accompanied by repeated gelatinous and bloody evacuations, and vomiting
of bilious matter. The strength became gradually less, and the animal
died three hours after the injection.
_Post-mortem appearances._ The lungs were found inflamed in a very
peculiar manner. They were gorged with blood, of a violet or black
colour, and presented many petechial spots, like small ecchymoses.
These spots existed also on the left ventricle of the heart, in the
spleen, in the mesenteric glands, in the gall-bladder, and even in the
subcutaneous cellular tissue. The peritoneum contained some spoonsful
of a reddish serum; but the mucous membrane of the digestive organs was
found to have been principally affected. In the stomach it was slightly
inflamed. In the intestines, but especially in the duodenum and rectum,
it was of a livid colour, presenting many black spots, and covered by a
gelatinous and bloody secretion, resembling lees of wine. The tissues
in these parts were slightly thickened.
EXPERIMENT XIV.
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