Reviewing the preceding summary of this interesting case, it seems evident that at least one advantage was gained from the use of the remedy--the awful malady was stripped of its horrors; if not less fatal than before, it was reduced to less than the scale of suffering which precedes death from most ordinary diseases. It must be remembered, too, that in this, the first case ever so treated, I possessed no data to guide me as to the dose or manner of administration of the drug. The remarkable cases of tetanus detailed in the sequel throw light on these important points, and will lead, in future cases, to the unhesitating administration of much larger quantities than at first I ventured to employ. I am not, however, rash enough to indulge the hope which involuntarily forces itself upon me, that we will ever from this narcotic derive an effectual remedy for even a solitary case of this disease; but next to cure, the physician will perhaps esteem the means which enable him “to strew the path to the tomb with flowers,” and to divest of its _specific_ terrors the most dreadful malady to which mankind is exposed. While the preceding case was under treatment, and exciting the utmost interest in the school, several pupils commenced experiments on themselves to ascertain the effects of the drug. In all, the state of the pulse was noted before taking a dose, and subsequently the effects were observed by two pupils of much intelligence. The result of several trials was, that in as small doses as a quarter of a grain the pulse was increased in fulness and frequency; the surface of the body glowed; the appetite became extraordinary; vivid ideas crowded the mind; unusual loquacity occurred; and, with scarcely any exception, great aphrodisia was experienced.