On the Preparations of the Indian Hemp, or Gunjah (Cannabis Indica): Their Effects on the Animal System in Health, and Their Utility in the Treatment of Tetanus and Other Convulsive DiseasesO'Shaughnessy, W. B.
Science
On the Preparations of the Indian Hemp, or Gunjah (Cannabis Indica): Their Effects on the Animal System in Health, and Their Utility in the Treatment of Tetanus and Other Convulsive Diseases
O'Shaughnessy, W. B.
Cannabis -- Physiological effect; Cannabis -- Therapeutic use
A blister to the nape of the neck, leeches to the temples, and
nauseating doses of tartar emetic with saline purgatives have rapidly
dispelled the symptoms in all the cases I have met with, and have
restored the patient to perfect health.
_Conclusion._
The preceding cases constitute an abstract of my experience on this
subject, and constitute the grounds of my belief that in hemp the
profession has gained an anti-convulsive remedy of the greatest value.
Entertaining this conviction, be it true or false, I deem it my duty
to publish it without any avoidable delay, in order that the most
extensive and the speediest trial may be given to the proposed remedy.
I repeat what I have already stated in a previous paper--that were
mere reputation my object, I would let years pass by, and hundreds of
cases accumulate before publication; and in publishing I would enter
into every kind of elaborate detail. But the object I have proposed
to myself in these inquiries is of a very different kind. To gather
together a few strong facts, to ascertain the limits which cannot be
passed without danger, and then pointing out these to the profession,
to leave them to prosecute and decide on the subject of discussion,
such seems to me the fittest mode of attempting to explore the
medicinal resources which an untried remedy may afford.
It may be useful to add a formula for making the preparations which I
have employed.
The _resinous extract_ is prepared by boiling the rich, adhesive tops
of the dried _gunjah_, in spirit (sp. gr. 835), until all the resin
is dissolved. The tincture thus obtained is evaporated to dryness by
distillation, or in a vessel placed over a pot of boiling water. The
extract softens at a gentle heat, and can be made into pills without
any addition.
The _tincture_ is prepared by dissolving the extract in spirit of 835°
density.
_Doses, &c._--In _tetanus_ a drachm of the tincture every half hour
until the paroxysms cease, or catalepsy or narcotism is induced. In
_hydrophobia_ I recommend the resin in soft pills, to the extent of ten
to twenty grains to be chewed by the patient, and repeated according
to the effect. In _cholera_, thirty drops of the tincture every half
hour will be often found to check the vomiting and purging, and bring
back warmth to the surface. My experience would here lead me to prefer
_small_ doses of the remedy in order to excite rather than narcotise
the patient.
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