conception of it. Of course if the _fact_ were indisputably proved one would only have to accept it, and endeavour, if possible, to discover the why and how. But the fact, which once looked so solidly established, is taking on a more and more insubstantial appearance in the light of closer investigation. The argument against Lamarckism rests on the basis (1) artificial experiment, (2) of observation of nature under normal conditions. As to the evidence from experiment, opinions fluctuated for some time—Darwin was disposed at one time to deny, at another to admit the alleged proofs it offered. In the present day opinion is overwhelmingly against the validity of these proofs. The cases where artificially produced mutilations are said to have been inherited have, when investigated, turned out to be by no means as clear and trustworthy as was supposed, nor can one place much reliance on a few cases of striking coincidence such as are certain to occur from time to time.[59] The adverse instances are very clear indeed. Chinese girls are never born with abnormally small feet. Jews are not born circumcised. Among tribes where tattooing is practised, no traces of this embellishment are ever found to be inherited. If it is a physiological law that the disuse of an organ not only atrophies it in the individual but (by inheritance of the atrophy) eliminates it from the species, there is no apparent reason why this law should not operate in cases where the organ is artificially removed. Yet it rarely or never seems to do so. Experiments upon animals, such as breeding for many generations from mice whose tails have been cut off, have never resulted in producing a clear case of inherited mutilation. A strong presumption is therefore raised that the effects apparently due to use and disuse under natural conditions (as in the eyeless fishes of the Kentucky caves) must be set down to some other cause. The queens in colonies of ants and bees have never exercised the functions of workers for thousands of centuries, yet they transmit these functions unimpaired.