_The Effects of Alcohol on the Digestive System and Metabolism._—The local action of alcoholic liquids is particularly destructive on an empty stomach; and when taken in strong solution, but it is also known that smaller doses, taken continuously, are liable to effect the digestive organs in a slower though similar way. The injurious effects of alcohol are that it acts as a local irritant, producing dilatation of the blood-vessels of the stomach and subsequent gastritis; it leads to hyperacidity, by stimulating the secretion of hydrochloric acid; the tartrates and malates contained in wine are decomposed in the stomach, setting free organic acids, and thus producing acidity; the acetic acid and yeast in beer set up an acetic acid fermentation in the stomach-contents. Whether taken alone or with food, the tendency of alcohol throughout is to lessen the churning movements of the stomach, and leads to atony of that organ, which in turn leads to dilatation of the stomach. Alcohol appears to have a particularly deleterious effect on the digestion of women. This is explained by the fact that men lead a more active outdoor life, and consequently retain their appetite for food longer than women. For the same reason, they are able to work off the effects of drinking more easily and start afresh the assimilation of food. The indoor life led by women, their clothing, worn tight around the stomach, are added causes for lack of appetite. Catarrh of the stomach results; this is followed by insufficient food and an increased amount of stimulants. There follow nausea, irregular and insufficient nutrition, indigestion, and a faulty elaboration of the food. By its action on the liver alcohol interferes with the amount and quantity of bile, and so inevitably leads to indigestion and constipation, and a similar interference with the action of the liver-cells and their chemical changes set up in many cases gouty conditions, accompanied by mental depression and irritability. Diseases of the liver occur more frequently as the result of taking frequent small doses of alcohol, though never reaching the stage of intoxication, than as the result of indulging more freely, but at longer intervals.