Since it is plain, that notwithstanding neither well-digested _pus_ was made use of, nor incisions made in the properest places, and it may be supposed few medicines were given; yet inoculation succeeded so as to bring on the distemper in a regular and mild manner, as appears by the cows with calf not slipping their calves. One may fairly conclude, that in this contagious distemper, like unto the small-pox, the practice of inoculation is not only warrantable, but much to be recommended. But how comes it then, that neither by application, digestion, nor inoculation, the distemper was not communicated in France? The Marquis says, that this distemper is not communicated but from one beast to another immediately. I must beg leave to say, that to my knowlege the distemper in February 1756 was carried from the farm-yard, where I visited some distempered cattle, to two other farm-yards, each at a considerable distance, without any communication of the cattle with each other, and merely by the means of servants going to and fro, or of dogs. The experiments made on four beasts, by tying over their heads part of distempered hides, or pieces of linen and woollen cloth or silk, which had received the breath and steams of dying cattle, serve to shew, by the bullock’s forcing off the cloth tied about him, that the putrid stench was disagreeable to him; but that neither his blood, nor that of the other three beasts, was then in a state to receive the infection. With regard to the pustules, which the Marquis relates were mixed with oats and bran, or dissolved in white wine; the distempered bile, which was mixed with milk; milk taken from diseased cows; water, in which part of a distempered hide had been steeped; and the precaution taken to force these mixtures into the paunch of calves, by means of a funnel, whose end was covered with a piece of raw distempered skin, that the beast might both swallow and suck in the disease. All these experiments could have no other effect than what followed; which was, that the acrimony of the distempered bile created first a _nausea_, and then produced a violent scouring, which killed the beast, leaving marks of its irritation on the intestines. The practice of inoculation is but lately followed, and even now but little known, in the provinces of France. Its advantages have not long since been strangely disputed at Paris. In the case of inoculating cattle, instead of a slip of raw hide taken from a beast just dead, or putting a pustule into the neck, they should either have passed in the dewlap cotton or silk dipped in well-digested _pus_, or have inserted in proper incisions cotton-thread or silk soaked with _pus_ either on the shoulders or buttocks; the true way of inoculating in the English manner. Some persons have indeed thought, that to inoculate with the blood of the infected would answer the intention; but most of the modern practitioners chuse to depend on digested matter.