Other investigators, however, have found no great difficulty in establishing nitrogenous equilibrium in man with much lower quantities of proteid food. Thus, Klemperer[18] found in the case of two young men of 64 and 65.5 kilos body-weight respectively, in an experiment lasting eight days, that nitrogenous equilibrium was established on 4.38 and 3.58 grams of nitrogen per day, but with a daily diet containing in addition to the small amount of proteid 264 grams of fat, 470.4 grams of carbohydrate, and 172 grams of alcohol, with a total fuel value of 5020 large calories. Peschel,[19] too, has reported experimental results showing that he was able to establish nitrogenous equilibrium for a brief period with 7 grams of nitrogen daily, 5.31 grams appearing in the urine and 1.58 grams in the fæces. Caspari and Glaessner,[20] in a five-days’ experiment with two vegetarians, found that the wife consumed daily, on an average, 5.33 grams of nitrogen, with fats and carbohydrates to equal 2715 calories, while the man took in 7.82 grams of nitrogen and 4559 calories. Both persons laid on nitrogen in spite of the low intake of proteid food. Siven’s[21] experiments, however, are perhaps worthy of more careful consideration. Of 60 kilos body-weight and 30½ years of age, his experiments conducted on himself extended through thirty-two days with establishment of nitrogenous equilibrium on 6.26 grams of nitrogen. Moreover, in another experiment he was in nitrogen equilibrium for a day or two at least on 4.5 grams of nitrogen. In Siven’s experiment, the most noticeable feature is the added fact that the total intake of food per day was comparatively low, with a fuel value of only 2444 large calories. In this connection we may call attention to the recent experiments of Landergren,[22] who found with four individuals fed on a daily diet containing only 2.1 to 2.4 grams of nitrogen, but with a large amount of carbohydrate, some fat and alcohol, that on the fourth day of this “specific nitrogen hunger” only 3 to 4 grams of nitrogen were metabolized and appeared in the urine. In other words, a healthy adult man having a sufficient intake of non-nitrogenous food seemingly need not metabolize more proteid than suffices to yield 3 to 4 grams of nitrogen per day.