But if you were to leave the blood in the pail for a few hours or for a
day, you would find, instead of the large jelly quite filling the pail,
a smaller but firmer jelly covered by or floating in a colourless or
very pale yellow liquid. This smaller, firmer jelly, which in the course
of a day or so would get still firmer and smaller, would in fact go on
shrinking in size, you may still call the =clot=; the clear fluid in which
it is floating is called =serum=.
What has taken place is as follows. Soon after blood is shed there is
formed in it a something which was not present in it before. This
something, which we call =fibrin=, starts as a multitude of fine tender
threads which run in all directions through the mass of blood, forming a
close network everywhere. So the blood is shut up in an immense number
of little chambers formed by the meshes of the fibrin; and it is this
which makes it seem a jelly. But each thread of fibrin as soon as it is
formed begins to shrink, and the blood in each of these little chambers
is squeezed by the shrinking of its walls of fibrin, and tries to make
its way out. The corpuscles get caught in the meshes, but all the rest
of the blood passes between the threads and comes out on the top and
sides of the pail. And this goes on until you have left in the clot very
little besides corpuscles entangled in a network of fibrin, and all the
rest of the blood has been squeezed outside the clot, and is then called
serum. =Serum, then, is blood out of which the corpuscles have been
strained by the process of clotting.=
Now I dare say you are ready to ask the question, If blood clots so
readily when it is shed, why does it not clot inside the body? Why is
our blood ever fluid? This is rather a difficult question to answer.
When blood is shed from the warm body it soon gets cool. But it does not
clot and become solid because it gets cool, as ordinary jelly does. If
you keep it from getting cool it clots all the same, in fact quicker,
and if kept cold enough will not clot at all. Nor does it clot when
shed, because it has become still, and is no longer rushing round
through the blood-vessels. Nor is it because it is exposed to the air.
Perhaps we don’t know exactly why it is, and you will have much to learn
hereafter about the coagulation of blood. All I will say at present is
that as long as the blood is in the body there is something at work to
keep it from clotting. It does clot sometimes in the body, and
blood-vessels get plugged with the clots; but that constitutes a very
dangerous disease.
=24.= Well, blood is thicker than water because it contains solid
corpuscles and fibrin. But even the serum, _i.e._ blood out of which
both fibrin and corpuscles have been taken, is thicker than water.
You know that if you were to take a basinful of pure water and boil it,
it would boil away to nothing. It would all go off in steam. But if you
were to try to boil a basinful of serum, you would find several curious
things happen.
Public-domain text, read in full here on John Shaqi.
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