Piebald rats and selection : $b An experimental test of the effectiveness of selection and of the theory of gametic purity in Mendelian crossesCastle, William E. (William Ernest)
Science
Piebald rats and selection : $b An experimental test of the effectiveness of selection and of the theory of gametic purity in Mendelian crosses
Castle, William E. (William Ernest)
Heredity
If one examines the horizontal rows of Table 15, he finds in general
that numbers increase toward the right. Exceptions are commonest toward
the ends of the rows where fewest individuals are represented. This
increase means that, within any generation, as the grade of the parents
rises, that of their offspring rises also. Since in general the selected
parents are _above_ the general average of the race for the time being,
regression is naturally downward in nearly all cases.
From what precedes we may conclude (1) that in this series of rats the
somatic character (appearance) of an individual is in general a true
indication of its germinal character, since the higher the grade of the
parents the higher the grade of the offspring, and _vice versa_; but
that (2) the somatic character of an individual is not a _perfect_ index
of its germinal character, since the offspring of aberrant individuals
are less aberrant than themselves, _i. e._, the offspring regress toward
the mean of the race; yet that (3) by selection of plus variations we
can displace, in a plus direction, not only the mean of the race, but
also the upper and lower limits of its variation, the total amount of
variability (standard deviation) being thereby only slightly decreased.
MINUS SELECTION SERIES.
This series begins with selected parents ranging in grade from -1.25
to -1.87. Their average, if each pair is weighted in proportion to the
number of its offspring, is -1.46. The offspring (Table 16), like the
offspring of the original plus selections, regress toward grade 0. They
range in grade from +0.25 to -2.00, their mean being -1.00. The total
number of offspring recorded in this generation is only 55, this being
too small to warrant the calculation of a correlation coefficient.
Generation 2 (Table 17) is somewhat larger, but still too small to make
statistical constants based upon it of much consequence. The offspring
show substantially the same range of variation as in the previous
generation, but with a slightly higher average (-1.07). The coefficient
of correlation (-0.03) is negative, but too small to be significant. The
record of the next eleven generations will be found summarized in Tables
18 to 28, or in more condensed form in Tables 29 and 30. Generation 13
(Table 28) is still incomplete.
Public-domain text, read in full here on John Shaqi.
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