_May 20._—Harry brought me home last evening a letter from Dr. Cox; my hand trembled as I took it. It was kind, giving the necessary information, but perfectly non-committal as to advice. I carried the letter over this morning to the lady friend who had promised to help me pecuniarily. I made up my mind fully to undertake the study if she fulfilled her promise, and already I felt separated from the rest of womankind; I trembled and hoped together. But alas for promises and plans; she offered to lend me 100 dollars—when I am told that I shall want 3,000 dollars! I did not express my disappointment, but asked who would be likely to assist further? She did not know, but thought the plan I had suggested of teaching, and laying up money for a few years, decidedly the best. Thrown thus entirely on my own resources, I finally resolved to accept a teacher’s position in a school in North Carolina, where, whilst accumulating money for future use, I could also commence a trial of medical study, for the Rev. John Dickson, who was principal of the school, had previously been a doctor. My old diary of those years, still existent, vividly portrays the anxiety and painful effort with which I left the family circle and ordinary social life, and took the first step in my future medical career. I felt that I was severing the usual ties of life, and preparing to act against my strongest natural inclinations. But a force stronger than myself then and afterwards seemed to lead me on; a purpose was before me which I must inevitably seek to accomplish. My own family showed the warmest sympathy with my plans. It was before the time of railways; the roads through Kentucky were little travelled; several rivers had to be forded, and three lines of mountains to be crossed. Two of my brothers determined to drive me to my unknown destination amongst the mountains of North Carolina. So the carriage was packed with books and comforts for the eleven days’ journey, and on June 16, 1845, with loving good-byes and some tears, in spite of strong efforts to restrain them, I left home for Asheville, North Carolina, to begin preparation for my unknown career. I find interesting details of that long drive, when every day took me farther and farther away from all that I loved. We forded more than one rapid river, and climbed several chains of the Alleghanies in crossing through Kentucky and Tennessee into North Carolina. The wonderful view from the Gap of Clinch Mountain, looking down upon an ocean of mountain ridges spread out endlessly below us, and seen in the fresh light of an early morning, remains to this day as a wonderful panorama in memory.