The most remarkable events that befell the Serampore Mission from this time were either domestic, or related to their connection with the College at Fort William, and the sanction they received from Government. Lord Wellesley went home in 1805, Colonel Bie died the same year, and these were most serious losses to the cause of the Serampore mission. Lord Wellesley had followed his own judgment, and carried things with a high hand, often against the will of the East India Company, and there was a strong desire to reverse his policy. His successor, Lord Cornwallis, died two months after landing, and Sir George Barlow, who carried on the government in the interregnum, though a good man, had not force enough to withstand the dislike of the Anglo-Indians to the mission. Mr. Ward made an attempt at Calcutta to preach in Hindoo in a chapel, the ground of which had been purchased by the missionaries, but as he walked through the streets the people shouted, "That's the Hindoo padre; why dost thou destroy the caste of the people?" And when, two Sundays later, a preacher of Brahmin birth appeared, there were loud cries of indignation. "O vagabond," cried one man, "why didst thou not come to my house? I would have given thee a handful of rice rather than that thou shouldst have become a Feringhee!" In spite of these cries, however, the chapel was thronged, until, after the third Sunday, when an order came forth from the magistrates, forbidding the missionaries either to preach, allow their converts to preach, distribute tracts, or even argue with the natives--or in anyway "interfere with their prejudices"--in Calcutta; and two new missionaries, named Chater and Robinson, who had come out without a licence, were prohibited from proceeding to Serampore. Considering that these orders emanated only from a Provisional Government during an interregnum, and that there was every hope that they might be reversed by the next Governor-General, the missionaries resolved to submit to them for the time, and to abstain from working in Calcutta. Early in the year 1806, however, the animosity of the English East Indians was increased by a mutiny that broke out among the Sepoys at Vellore, in the Madras Presidency, in consequence of some regulations as to their dress, which they resented as being supposed to assimilate them to Europeans. The English colonel and all his garrison were massacred, and, though the mutineers were surrounded and destroyed, great alarm prevailed. The discontent of the Sepoys was attributed to their displeasure at the spread of Christianity, and it was even averred that the lives of the English in India could only be preserved by the recall of all the missionaries!