On the arrival of the steamship _Taisang_ from Amoy at the Mariveles Quarantine Station at about 6.30 A.M. on April 30, 1912, the entire personnel was carefully examined and found free from sickness of a suspicious nature and from elevations of temperature. Seventy-three persons were detained to serve a quarantine detention of seven days. On the evening of April 30, a Chinese passenger, aged fifty-one years, was found to have a temperature of 39° C. with a pulse of 100. He was placed in the hospital, but protested vehemently that he was not sick. He was carefully watched from the first; there was a slight cough; physical examination of the chest revealed a few râles; smears made of the sputum and stained for plague bacilli were negative. On the fifth day, the fever still persisted, but the patient stated that he did not feel ill and demanded to be released from the hospital. On this day, the expectoration was blood-stained, but no suspicious organisms could be found in the smears nor could any physical signs of pneumonia be detected. Furthermore, there were no palpable glands. On the morning of the seventh day, the temperature and pulse dropped and the general condition was distinctly worse. The patient now admitted that he felt ill. Several hours later, he flinched when pressure was made in the right axilla. Lymphatic enlargement was now made out, and by the evening of the seventh day the bubo in the axilla had increased markedly in size, the swelling approximating 3 by 7 centimetres. Glands now became palpable in other portions of the body, particularly in the cervical region, and a few hours later there were inguinal and femoral buboes. The patient became rapidly worse, and died at 7 o'clock on the morning of the eighth day of his illness. At the necropsy, the glands of the right axilla and those of the right side of the neck were found enlarged; the other lymphatic glands were also enlarged, but to a lesser degree. There was consolidation of the lower lobe of the right lung, and the spleen was about twice its normal size. In brief, the necropsy findings of a typical case of septicæmic plague were present. Smears from the spleen and the right axillary gland showed immense numbers of bipolar-staining organisms. Cultures made from fresh pieces of tissues and later inoculated into animals gave positive results for plague. BEGINNING OF THE MANILA EPIDEMIC.--Proceeding with the Manila epidemic inaugurated with the two cases referred to as recorded in June, 1912, we find that the total number of cases recorded from the time of the outbreak in 1912 until the last case in 1914 was 90. (This includes none of the imported cases from China which developed en route to Manila from Chinese ports.)