For wine is the most beneficial of all drinks, the pleasantest medicine in the world, and of all dainties the least cloying to the appetite, provided more regard be given to the opportunity of the time of drinking it than even to its being properly mixed with water. Water, not only when it is mixed with wine, but also if it be drunk by itself between mixed wine and water, makes the mingled wine the less hurtful. We should accustom ourselves therefore in our daily diet to drink two or three glasses of water, which will allay the strength of the wine, and make drinking of water familiar to our body, that so in a case of necessity it may not be looked on as a stranger, and we be offended at it. It so falls out, that some have then the greatest inclination for wine when there is most need they should drink water; for such men, when they have been exposed to great heat of the sun, or have fallen into a chill, or have been speaking vehemently, or have been more than ordinarily thoughtful about any thing, or after any fatigue or labor, are of the opinion that they ought to drink wine, as if nature required some repose for the body and some diversion after its labors. But nature requires no such repose (if you will call pleasure repose), but desires only such an alteration as shall be between pleasure and pain; in which case we ought to abate of our diet, and either wholly abstain from wine, or drink it allayed with very much mixture of water. For wine, being sharp and fiery, increases the disturbances of the body, exasperates them, and wounds the parts affected; which stand more in need of being comforted and smoothed, which water does the best of any thing. If, when we are not thirsty, we drink warm water after labor, exercise, or heat, we find our inward parts loosened and smoothed by it; for the moisture of water is gentle and not violent, but that of wine carries a great force in it, which is no ways agreeable in the fore-mentioned cases. And if any one should be afraid that abstinence would bring upon the body that acrimony and bitterness which some say it will, he is like those children who think themselves much wronged because they may not eat just before the fit of a fever. The best mean between both these is drinking of water. We oftentimes sacrifice to Bacchus himself without wine, doing very well in accustoming ourselves not to be always desirous of wine. Minos made the pipe and the crown be laid aside at the sacrifice when there was mourning. And yet we know an afflicted mind is not at all affected by either the pipe or crown; but there is no body so strong, to which, in commotion or a fever, wine does not do a great deal of injury.