The transactions of the last winter almost completely served to undermine the small strength of constitution he had left; he was constantly harrassed by complaints in the organs of digestion; head ache deprived him of the power of application; his countenance assumed a sallow complexion; the eye which had beamed with animation, retired within its socket, deprived of lustre; melancholy conceptions filled his imagination more habitually, and were excited by slighter causes; at times, they altogether deprived him of the power of exertion; and while he lamented their effect, the contemplation of themselves rendered him the more their prey. At this time, a gloomy day, or the smallest disappointment, gave him inconceivable distress; but he was not altogether incapable of temporary relief, and the few moments of pleasure he seemed to enjoy, would have given reason to believe, that he might once more have recovered, and have long continued to be the delight and instructor of his friends. A more close observation would at the same time have justified the supposition, that the strong and painful emotions of mind he had suffered, had already induced disorders of the bodily system, which were irrecoverable. Before Doctor Garnett had left his situation at Glasgow, he had determined to practice as a physician in London; but from this he was restrained, during the time he was at the Royal Institution. To his former intention he now determined to apply himself, and in addition to the attempt, by giving private lectures, to assure himself of that independency, of which his unfortunate destiny, though with every reasonable expectation before him, had hitherto deprived him.