With this intention, he purchased the lease of a house in Great Marlborough Street; and in the summer of 1801, built a lecture room. He brought his family to town, and once more looked forward with hope. The flattering success he soon met with, and a short residence at Harrowgate in the autumn, contributed to afford a temporary renovation of health and spirits; it was, however, but a short and delusive gleam of prosperity which now dawned upon him; for, confiding too much in his newly increased strength, he exerted himself to a much greater degree than prudence would have suggested. In the course of the following winter, he delivered not less than eight courses of lectures, two on chemistry, two on experimental philosophy, a private course on the same subject, one on mineralogy, and the course to which this sketch is prefixed, which he also delivered in an apartment at Tom's Coffee house, for the convenience of medical students, and others, in the city. Besides these, he commenced two courses on botany, one at Brompton, and the other at his own house; but a return of ill health prevented his concluding them. It was not to be expected, that a constitution so impaired and debilitated, could long support this continued labour of composition and recitation; accordingly he became affected with a consequent disorder, which rapidly exhausted his strength; and, being unable to employ the only probable means of recovering it, he became more incapable of exertion. His spirits however were roused, and he ceased not to use every means of increasing his practice. In the spring of 1802, the office of physician to the St. Mary le Bonne Dispensary happened to be vacant, and he became a candidate; he was more than commonly anxious to obtain this situation. It seemed to him, as if his future good or ill fortune depended altogether upon the event of his canvass, he spared no effort to ensure his success; and accordingly was appointed to the situation in May. His life now drew near a close. Little was he calculated to bear the accumulated labours, and extreme fatigue, to which he was daily exposed. Any benefit which might have resulted from constant and well regulated occupation was frustrated; for whilst he still suffered from the vividness of his conception, representing to him in mournful colours the occurrences of his past life, he became liable to other evils, not less injurious and destructive. The practice of medicine requires both vigorous health of body and firmness of mind. Dr. Garnett, now greatly weakened in body, and not exempt from anxiety of mind, became more and more susceptible to the action of morbific matter. It was not long before he received the contagion of typhous fever, whilst attending a patient, belonging to that very dispensary of which he had been so anxious to become physician. He laboured under the disorder for two or three weeks, and died the 28th of June, 1802; and was buried in the new burial ground of the parish of St. James,