He was again admitted to the hospital, and the fracture dressed in the usual manner. After five or six days a gutta percha splint was used which encircled the arm. Bony union was slow in taking place. However, on Oct. 3d, nearly two months from the date of the fracture, he left the hospital, the union being complete, and he being entirely relieved from his pain; in fact, he was relieved from the moment of the fracture. This case presents a question in pathology which is of interest. Was there a localized periostitis at this point? If so, why was it not entirely relieved by the treatment which consisted of blisters and iodine, externally, and mercury and iodide potassium internally? Was there a deficiency of nutrition at this point? or anemia from some change in the nutrient artery,--the result of the periostitis of the long bones? Or was it incipient necrosis? Prof. Hamilton gives the record of a case of fracture of the humerus, from muscular action, taking place three several times in the same individual, each time in a different place. CASE THIRD.--Dec. 29th, 1878, was called to see Mr. ----, male, married, aged about 40 years. Has led an out-door, active life. Has always been healthy. No venerial taint. Nervous temperament, spare built, and weighs about 140 pounds. Present condition: Has been sick two or three days; the attack commenced with a chill, followed by fever; has had fever ever since the chill; complains of pains in the back and legs; has vomited considerable; bowels costive; tongue coated; severe pain in right side corresponding to lower part of the lung, which I found solidified; there is considerable cough. Ordered a cathartic; to be followed by an anti-pyretic of acetate of ammonia and aconite, and a blister over the lower part of the right lung. Continued this treatment for three or four days, when the pneumonia began to subside, and at the end of about ten days I considered my patient convalescent. About this time I was sent for in great haste after night. The patient, who is a very intelligent man, said he had felt worse during the day, and in the evening, his knee, which had been somewhat painful for two or three days, had become exceedingly painful. I gave morphine, hypodermically, and went home, leaving some morphine for the night. The next day I saw him. The pain had been relieved by the morphine, still occasionally it was quite severe. There was no redness or heat, or even tenderness; nothing unnatural about the knee except pain, which was aggravated by any attempt to move the leg.