Ordered quinine as a tonic, and pill "C. C." as a cathartic. Bandaged the leg pretty tightly from the toes to above the knee. The urine was natural; pulse and temperature only slightly elevated. After six or seven days of these symptoms, the knee began to feel hot and became very slightly swollen. Ordered a small blister over the inside of the knee as the greatest amount of pain seemed to be here. Dressed it with tartar-emetic ointment until the skin was very sore; using iodine on other puts of the knee. Used iodide potassium and colchicum, internally. This treatment for five days seemed to do no good. On Jan. 17th, twenty-two days from the beginning of his illness, and about twelve days from the first appearance of symptoms denoting any local trouble at the knee, a consultation was held, the result of which was a blister over the whole of the knee, to be dressed with unguentuin hydrargiri. The inflammation was but little influenced by this or any other treatment. The knee continued to slowly and surely enlarge. And this extended upward without first producing any great distention of the synovial sack under the patella. There seemed to be simply enlargement of all the tissues of the lower part of the thigh. This continued until about the 1st of Feb. when, from the general appearance of the patient, viz: a typhoid condition, feeble pulse, coated tongue, emaciation, loss of appetite, as well as from the local appearance of the inside of the knee, I suspected pus within the joint. Accordingly, I introduced an exploring needle into the inner part of the joint just above and anterior to the insertion of the tendon of the semimembranosis muscle. Finding pus, I made an incision only about half an inch long, and squeezed out perhaps an ounce of pus. Closed this up and again bandaged the leg. There was but very little pus discharged from this opening afterward, not, however, for want of drainage, since the cut was kept open by introducing the probe occasionally. About the 9th or 10th of Feb. fluctuation became quite apparent along the outer and lower part of the thigh. On Feb. 12th, consultation was again had, when fluctuation being very well marked over a considerable portion of the thigh in its lower and middle thirds, after giving the patient chloroform, an incision was made three inches long on the outer and posterior part of the thigh, from the junction of the lower with the middle third, downward through the posterior part of the vastus externus muscle. About two quarts of laudable pus was discharged. By introducing the finger upward and downward, the periostium could be felt smooth except within the knee joint, for this could be distinctly felt, the finger passing readily between the ends of the femur and tibia, and beneath the patella; the crucial and lateral ligaments seemed to be gone, and the cartilages somewhat roughened. A drainage tube was put in, the leg bandaged from the toes to the trochanter