Nor is it possible to conclude from the experiments and observations cited that the body remains indifferent to polluted air until the latter has reached a certain definite saturated condition. There can be little doubt but that a degree of pollution far short of that necessary to produce death has a weakening effect on the human organism, and that by means of the increased functional activity of other organs doing work intended for the lungs the resistance to disease is much impaired. Life is a continual struggle of the bodily tissues against the attacks of the micro-organisms and their tendencies to destroy life; hence inadequate ventilation or any other condition which interferes with the normal action of the organs of the body causes weakness and affords opportunity for the attack of some disease-producing germ. It stands to reason that an individual whose lung tissues have become soft and incapacitated must be more liable to succumb to disease than another whose lung capacity is large and whose blood has been continually and sufficiently oxygenated. Perhaps no more impressive proof of this is seen than in the ravages of consumption, which is so prone to attack those whose vitality is diminished by living in unhealthy and unventilated cellars or in crowded tenements. Statistics are very definite on the subject of tuberculosis among Indians, who rarely suffer from the disease when living in tents or on the open prairie, but when they become semi-civilized and crowd together in houses heated through the winter months by stoves, the germs of tuberculosis take firm hold, and the deaths from this disease are greater in proportion to population among this race than anywhere else. _Effect of change in air._ This discussion illustrates another law of disease which makes the necessity for ventilation particularly great among rural communities where for nine months in the year outdoor life is freely enjoyed, namely, that when either an individual or people are brought under changed conditions, perhaps not unwholesome to those accustomed to them, those unaccustomed will suffer severely. So a lack of ventilation during the winter months in a farmhouse is very serious in its consequences to those who have had the full enjoyment of fresh air through the rest of the year. Reference has already been made (in Chapter 1) to the prevalence of influenza in rural communities, and it is quite probable that this would be largely eliminated if the lungs were not deprived of their oxygen as they are in most houses on the farm. _Composition of air._