Another reason why it is difficult to make a room an air-tight chamber is that if a stove or fire-place be in the room, a strong suction is produced through the flame, and such suction requires the entrance of outside air. It is a common experience that a fire-place in a room otherwise tight will refuse to draw and will smoke persistently until a door or window is opened, when, a supply of air being provided, the fire is made bright and active. Fortunately, the vitiation of the air in a room is never so severe as that in an experimental chamber, and there are few examples which can be cited of men or women dying from lack of ventilation in an ordinary room. But the serious aspect of inadequate ventilation is not that it actually induces death, but that it decreases the powers and activities of the various organs of the body; that it interferes with their normal processes, that it loads up in the body an accumulation of organic matter which is normally oxidized by fresh air and which, if not oxidized, obstructs the activities of other organs of the body. _Danger of polluted air._ Unfortunately, it is not possible to detect by the physical senses that point at which the human organism suffers from insufficient ventilation. Some years ago, Dr. Angus Smith built an air-tight chamber or box in which he allowed himself to be shut up for various lengths of time in order to analyze his own sensations on breathing vitiated air. He found that, far from being disagreeable, the sensation was pleasurable, and he says, "There was unusual delight in the mere act of breathing," although he had remained in the chamber nearly two hours. On another occasion he stayed in more than two hours without apparent discomfort, although after opening the door, persons entering from the outside found the atmosphere intolerable. He placed candles in the box, which were extinguished in a hundred and fifty minutes, and a young lady, who was interested in the experiment, going into the box as the candles went out, breathed it for five minutes easily; she then became white, and could not come out without help.