The first event that fixed the attention of Northern men seriously upon the subject of slavery, over which they had slumbered since 1808, was the dispute that arose in 1819, upon the proposal to admit Missouri into the Union as a slave State. The contest was a vehement one. Mr. Webster was _then_ upon the side of liberty. He led the van of the opposition that arrayed itself in New England, and would have averted the catastrophe, but for the cry “dissolution of the Union,” then first raised at the South, and the necromancy of Henry Clay, who, with his wand of compromise, conjured the people into acquiescence. Words, however, significant words, touching the evil and the awful wrong of slavery, were uttered in that controversy which were not to be forgotten. And feelings of compassion for the bondmen were awakened which were not allayed by the result. Shortly before the Missouri controversy a movement had commenced in the slave States, which was pregnant with effects very different from those intended by the projectors of it. Often was it roughly demanded of us Abolitionists, “Why we espoused so zealously the cause of the enslaved?” “why we meddled so with the civil and domestic institutions of the Southern States?” Our first answer always was, in the memorable words of old Terence, “Because we are men, and, therefore, cannot be indifferent to anything that concerns humanity.” Liberty cannot be enjoyed, nor long preserved, at the North, if slavery be tolerated at the South. But to those who felt so slightly the cords of love and the bonds of a common humanity that they could not appreciate these reasons, we gave another reason for our interference with the slavery in our Southern States, even this: _we were solicited, we were urged, entreated by the slaveholders themselves to interfere_.