Studies on Epidemic Influenza: Comprising Clinical and Laboratory InvestigationsUniversity of Pittsburgh. School of Medicine
History
Studies on Epidemic Influenza: Comprising Clinical and Laboratory Investigations
University of Pittsburgh. School of Medicine
Influenza; Influenza Epidemic, 1918-1919
The great frequency and the high
mortality of broncho-pneumonia were particularly noted during the
present epidemic. During the present epidemic the great mortality among
pregnant women was another striking feature, and yet this is by no means
new, having been recorded by some of the earliest writers. Such also may
be said of the recurrence of the disease in the same patient. One
important observation brought out in the study of the pandemic of 1889
to 1892 was that the ordinary infections occurring in the spring and
fall known as grippe or La Grippe are in no way connected with the
pandemics which have occurred. There seems to be a consensus of opinions
among the records of the more recent epidemics, as well as during the
present pandemic, that weather conditions in no way influence the spread
of the disease. Furthermore, a study of weather conditions throughout
the United States, and particularly those of our own city, seem to bear
out the truth of this observation. While clinicians during other
epidemics expressed their belief in the incident of a primary case
producing infection, it has only been during the present one that such
an opinion has not been assailed. The large number of military training
camps and cantonments have undoubtedly offered splendid opportunity for
the spread of influenza. The futility of attempting to control it even
under normal conditions is still questionable. Consistent with former
reported invasions of the disease, the present epidemic lasted a
definite period. This period was about six weeks in most of our large
cities, colleges and institutions, extending approximately from October
1 to November 15.
It is imperative to note the accurate clinical observations recorded
from the numerous epidemics of the past by men with far less data to go
upon than is available at the present day. The high morbidity among the
personnel of many of our hospitals and institutions where the infection
occurred and the relatively low mortality deserve attention. This may be
partly explained by the methods of treatment of those infected, but not
entirely. The great likelihood of carriers of influenza, who either are
not ill or who are suffering from very mild infection, is an observation
also noted by former writers which cannot be ignored. The value of the
masks has not been established, although they have been extensively used
in many parts of the country. Frequent throat lavage was generally
accepted as a rational preventive measure. Relightings of the disease
have been noted in most of our cities after the subsidence of the
epidemic. Vaccination against influenza is fully discussed in Dr.
Haythorn’s paper in this series.
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