I am not able to give you any very positive expression of opinion on the matter respecting which you write, but I can say that I have smoked tobacco and taken wine for years, and though I cannot aver that I should not have done as well without them, I have felt comforted and sustained in my work by both at times, especially by the weed. However, I was very well in the last campaign in South Africa, where for some time we had neither wine nor spirits. Climate has a good deal to say to the craving for a stimulant, and men in India, who never drink in England, there consume "pegs" and cheroots enormously. Of course, tobacco is to be put out of account in relation to great workers and thinkers up to the close of the middle ages, but the experience of antiquity would lead one to infer that the moderate use of wine, at all events, was not unfavourable to the highest brain development and physical force. Bismarck and Moltke are very great smokers; neither is a temperance man. In effect, I am inclined to think that tobacco and stimulants are hurtful mostly in the case of inferior organizations of brain physique, where their use is only a concomitant of baser indulgences, and uncontrolled by intelligence and will. I am quite in favour, therefore, of legislative interference, and almost inclined to supporting the Permissive Bill. W. H. RUSSELL. Feb. 23, 1882. (For) MR. JOHN RUSKIN. You are evidently unaware that Mr. Ruskin entirely abhors the practice of smoking, in which he has never indulged. His dislike of it is mainly based upon his belief (no doubt a true one) that a cigar or pipe will very often make a man content to be idle for any length of time, who would not otherwise be so. The excessive use of tobacco amongst all classes abroad, both in France and Italy, and the consequent spitting everywhere and upon everything, has not tended to lessen his antipathy. I have heard him allow, however, that there is reason in the soldiers and the sailors' pipe, as being some protection against the ill effects of exposure, etc. As to the effect of tobacco on the brain, I know that he considers it anything but beneficial. Feb. 12, 1882. KESHUB CHUNDER SEN.