The Alumni Journal of the College of Pharmacy of the City of New York, Vol. II, No. 2, February, 1895 — John Shaqi
The Alumni Journal of the College of Pharmacy of the City of New York, Vol. II, No. 2, February, 1895Various
History
The Alumni Journal of the College of Pharmacy of the City of New York, Vol. II, No. 2, February, 1895
Various
College of Pharmacy of the City of New York -- Alumni and alumnae -- Periodicals; Pharmacology -- Periodicals
The author employs the official ingredients and quantities and heats
the lard oil to 100° C., removes heat, and adds the nitric acid without
stirring and reapplies heat when effervescence ceases until all gas is
expelled. It is best to use a vessel of six times the capacity of the
quantity to be made to allow for the copious effervescence which takes
place. When the foregoing mixture has cooled to 40° C., the solution of
mercuric nitrate is added and the temperature is raised gradually to
60° C., and maintained until no further evolution of gas is noticed. If
it is then agitated until cold, as usual, the resulting product will
comply with the requirements of the Pharmacopœia.
Ointment made by the U. S. P. method, which has become spongy, may
be remedied by elevating the temperature to 60° C. and cooling with
agitation.
_Typical Bacilli._--_E. Klein_ [_Quart. Jour. Micros. Sci._, 1894,
1-9 (1 _pl_)] concludes from observations on the bacilli of anthrax
diphtheria, and tubercle, that these species are not such typical
bacilli as they are usually represented to be. For though under
many conditions their morphological characters are those of typical
bacilli, yet under others they revert to or assume forms indicating
their relationship to Saccharomyces or a still higher mycelia fungus.
In the case of anthrax, the typical bacilli may be represented by
oval and spherical bodies, some of which may contain vacuoles, and
under conditions (early stages of growth on plates composed of beef
bouillon, gelatin 10 per cent., pepton 1 per cent., salt 1 per cent.),
the colonies are composed of large spindle-shaped, spherical or
oval elements in which vacuolation is frequent. Similar appearances
are to be observed in colonies of the thrush fungus. From this it
is inferred that while _B. anthracis_ is a typical bacillus as a
pathogenic microbe, yet in its early stages of growth on gelatin
it may assume characters having much resemblance to _Saccharomyces
mycoderma_ or _Oidium_ and thus return temporarily to an atavistic
stage in its evolutionary history. With regard to _B. diphtheriæ_
the author points out that the club-shaped expansions of one or both
ends are not to be regarded as due to involution, for both under
natural and artificial conditions where there is active growth these
expansions will be found, and have moreover a striking resemblance to
the ends of growing hyphæ. Their existence, therefore, is only to be
explained by their representing a relationship to a mycelial fungus.
In the case of the tubercle bacilli, preparations not unfrequently
show threads or filaments composed of unequal elements, some of them
being conspicuous for knob-shaped expansions, similar to those of
diphtheria. Such appearances occur not only in sputum but in artificial
cultivations e.g. glycerin agar after some weeks incubation at 37°.
All these preparations behave in the same way as _B. tuberculosis_
when treated with appropriate staining reagents; and that they are not
Public-domain text, read in full here on John Shaqi.
Reviews
Reviews
No reviews yet
Be the first to share your thoughts on this work.
Join the Discussion
Join the discussion
Sign in to leave a comment or review.
Sign InorCreate an account