_Novaspirin_ is the name applied to methyl citric acid ester of salicylic acid. It occurs as a white powder having a slightly acid taste. It is nearly insoluble in water but is readily soluble in alcohol. Novaspirin may be given in doses of 1 gramme three times a day. (_Phar. Zeit._, 1907, page 9.) _Quinine Phytinate._—Anhydro oxymethylene diphosphate of quinine occurs as a yellow powder, very soluble in water but almost insoluble in alcohol, ether, benzin or chloroform. The substance contains 57 per cent. of quinine and has an intensely bitter taste. _Scarlatin Marpman_ is an antitoxin preparation that, given internally, is being used as a prophylactic for scarlet fever. It is said to be produced by inoculating animals with infectious material from scarlet fever patients and inoculating other animals with the serum taken from the first. The serum from the blood of the second animal is used to immunize other animals, and it is from these immunized animals that the antitoxin serum is prepared. Scarlatin is a yellowish, opalescent liquid having a slight odor and a salty taste. The substance has a specific gravity of from 1·012 to 1·013, is neutral in reaction and gives a copious precipitate with reagents for albumin. (_Phar. Centralh._, 1907, page 69.) _Solubility of Salicin._—D. B. Dott (_Phar. Jour._, 1907, page 79) finds that the solubility of salicin, as given in the British Pharmacopœia (1 in 28) is practically correct, while that of the U. S. P. (1 in 21 at 25° C.) is too high. Using pure salicin, that melted at 201° C., he finds that it has a solubility of 1 in 24 at 25° C., or very nearly that called for by the British Pharmacopœia at ordinary temperatures. _Substitutes for Cocaine._—Dr. Hugo Wintersteiner (_Wiener Mea. Wochensch._, 1906, page 1339) reports a comprehensive comparative study of the use of cocaine and its various substitutes in eye work. Of the numerous substances that have been proposed from time to time he describes tropococain, holocain, eucain, stovain, alypin and novocain at some length and concludes that while it is true that these substances are relatively more stable than cocain, and are therefore more readily sterilized, the numerous objectionable features, such as unreliability, irritating properties and the production of a hyperemia, are so much more objectionable that cocaine must be admitted to be by far the most satisfactory as well as the safest local anesthetic in all varieties of eye work. _Tannisol_ is a reddish-brown, odorless and tasteless powder that is insoluble in water, ether or benzine, but is soluble in alcohol and in dilute solutions of alkalies or of the alkaline carbonates. It is directed to be used internally in cases of intestinal catarrh, and externally for a variety of inflammatory conditions of the skin. Internally it may be given in doses of 0·50 gramme (_Phar. Centralh._, 1906, page 1006).