_Theolactin._—This name has been applied to a double salt of theobromin
sodium and sodium lactate. It occurs as a white hygroscopic powder,
readily soluble in water and having a distinctly bitter taste. It is
said to be an active diuretic, but is not free from occasional side
effects in the form of gastric disturbances. (_Phar. Zeit._, 1907, page
49.)
_Tinctura olea Europeae._—A tincture made with 60 per cent. alcohol from
the dried leaves of the European olive has been used as a febrifuge as
well as a general tonic in place of the tincture of cinchona bark.
_Triacetyl morphin._—This substance has been isolated from a mixture of
acetyl derivatives of morphin. Triacetyl morphin melts at from 206 to
208° C., is only slightly soluble in water or cold alcohol, but is
readily soluble in acids. With hydrochloric acid it forms a salt that
crystallizes in the form of long needles. (_Phar. Centralh._, 1906, page
928.)
_Tulaselactin_ is the name given by Behring to a substance that is
expected to immunize infants against tuberculosis. (_Phar. Centralh._,
1907, page 24.)
_Tulase_ (_A. J. P._, 1906, page 582) is the name given by Behring to
his immunizing and curative serum for tuberculosis.
This preparation is said to contain all of the constituents of the Koch
bacillus. It occurs as a clear fluid which has the general outward
characteristics of thin honey. It may be given subcutaneously,
intravenously or by mouth. The mixture of tulase with milk, mentioned
above, is the form in which it may be administered to infants.
Tulase is now being used in an experimental way, but Behring himself
warns against too much reliance being placed on the curative properties
of the substance.
CORRESPONDENCE.
_Editor of the_ AMERICAN JOURNAL OF PHARMACY.
DEAR SIR:—I send you herewith the result of the votes of the Committee
of Revision upon the first instalment of corrections in the U. S.
Pharmacopœia, eighth revision, since the passage of the Food and Drugs
Act.
Very truly yours,
JOSEPH P. REMINGTON,
_Chairman_.
CHANGES AND CORRECTIONS IN THE UNITED STATES PHARMACOPŒIA.
(Eighth revision.)
Belladonna Leaf _now_ 0·3 per cent. mydriatic alkaloids.
Belladonna Root _now_ 0·45 per cent. mydriatic alkaloids.
Colchicum Seed _now_ 0·45 per cent. of colchicine.
Ipecac _now_ 1·75 per cent. of ipecac alkaloids.
Stramonium _now_ 0·25 per cent. of mydriatic alkaloids.
Fluidextract of Belladonna Root _now_ 0·4 gramme alkaloids in 100 c.c.
Tincture of Belladonna Leaf _now_ 0·03 gramme alkaloids in 100 c.c.
Fluidextract of Colchicum Seed _now_ 0·4 gramme alkaloid in 100 c.c.
Tincture of Colchicum Seed _now_ 0·04 gramme alkaloid in 100 c.c.
Fluidextract of Ipecac _now_ 1·5 gramme alkaloids in 100 c.c.
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