The Biological Problem of To-day: Preformation Or Epigenesis?: The Basis of a Theory of Organic DevelopmentHertwig, Oscar
Science
The Biological Problem of To-day: Preformation Or Epigenesis?: The Basis of a Theory of Organic Development
Hertwig, Oscar
Developmental biology; Embryology; Genetics
The cell, which consists of protoplasm and a nucleus, is an elementary
organism, that, by itself, or in combination with other cells, forms the
basis of all animal and vegetable organisation. In minute structure it is
so extraordinarily complicated that its essential constitution (its
micellar or molecular structure) eludes our observation. It is a medley,
composed of numerous, chemically distinct particles that may be divided
into two groups, organised and unorganised. The latter are free, or in
solution; they are such as albuminates, fats, carbo-hydrates, water,
salts, and they serve as material for the nutrition and growth of the cell.
The former make up the living cell body (in the narrow sense). They are
able to multiply by growth and division, and they are therefore the
elementary parts, units of life of lower rank, of which the cell, a unit of
higher rank, is composed. They are the gemmules of Darwin, the
physiological units of Spencer, the bioblasts of Altmann, the pangenes of
De Vries, the plasomes of Wiesner, the idioblasts of Hertwig, and the
biophores of Weismann.
The cells of every organic species possess a proper, specific organisation,
more or less complicated, and, in correspondence with this, they are
composed of more or less numerous and varied organised particles.
The nucleus is a special organ of cells, which is always present. It
displays a collection of numerous, peculiar, elementary living units, the
idioblasts. These show chemical, morphological, and functional differences
from the plasomes, the living units of the protoplasm; but perhaps the
idioblasts, by absorption of different material, may transform themselves
into the plasomes, just as these last, by a similar process, may produce
the plasma-products. In my view, the nucleus is the bearer of the idioplasm
or hereditary material, that is to say, of a substance that is more stable
than protoplasm, and, because it is less subject to influences of the outer
world, it stamps its specific character upon the organism.[9]
A mass of protoplasm with several nuclei (like the myxomycetes,
coeloblasts, etc.) has the morphological value of a number of cells
(synergides), corresponding to the number of the nuclei.
The means by which the continuity of life is maintained is the capacity of
the cell to manifold itself by division, so forming two or more separate
pieces. The process, which in most cases is associated with complicated
changes of the nuclear contents, appears essentially to consist of the
following: The elementary units of the cell (centrosomes, chromatin bodies
in the case of nuclear division), being endowed with special energy
resulting from the processes of growth, divide, and the elementary products
of division separate into two groups, which move from the middle line;
upon this there follows a division of the general body of the cell, _i.e._,
of the protoplasm and its contents.
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